Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RBL2 All Species: 18.48
Human Site: S394 Identified Species: 33.89
UniProt: Q08999 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q08999 NP_005602.3 1139 128367 S394 L Q Q H F D K S K A L R I S T
Chimpanzee Pan troglodytes XP_523371 1139 128318 S394 L Q Q H F D K S K A L R I S T
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_535303 1139 128252 S394 L Q Q H F D K S K A L R I S T
Cat Felis silvestris
Mouse Mus musculus Q64700 1135 127455 S391 L Q Q H L D K S K A L R V C T
Rat Rattus norvegicus O55081 1135 127799 S391 L Q Q H L D K S K T L R V C N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520195 1071 120785 S367 S I A T H S L S R L H T M L K
Chicken Gallus gallus Q90600 921 104417 P220 Y F I K L S P P A M L K E P Y
Frog Xenopus laevis NP_001084880 998 113114 G297 K F V E F P I G N C T P R K Q
Zebra Danio Brachydanio rerio XP_002667000 970 107485 S269 S I V G T P V S S A M Q S V G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24472 845 96808 I144 D L D R K F S I T F M L H K R
Honey Bee Apis mellifera XP_395096 1006 113492 V305 N S K A I N R V Y E Q H V L S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa B9GLX8 1035 114624 L334 G L I Y Y E D L M E E S S L Q
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LKZ3 1013 112157 E312 P D G L T Y F E D L L E E T S
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.9 N.A. 97.1 N.A. 90.9 90 N.A. 79.8 21.8 43.2 53 N.A. 23.5 40.2 N.A. N.A.
Protein Similarity: 100 99.9 N.A. 98.7 N.A. 94.9 94.8 N.A. 87.1 38.3 61.2 65.5 N.A. 40.6 57.5 N.A. N.A.
P-Site Identity: 100 100 N.A. 100 N.A. 80 66.6 N.A. 6.6 6.6 6.6 13.3 N.A. 0 0 N.A. N.A.
P-Site Similarity: 100 100 N.A. 100 N.A. 86.6 73.3 N.A. 20 13.3 6.6 26.6 N.A. 6.6 33.3 N.A. N.A.
Percent
Protein Identity: 20.3 N.A. N.A. 21.8 N.A. N.A.
Protein Similarity: 39.6 N.A. N.A. 39.3 N.A. N.A.
P-Site Identity: 0 N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: 20 N.A. N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 8 0 0 0 0 8 39 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 8 0 0 0 16 0 % C
% Asp: 8 8 8 0 0 39 8 0 8 0 0 0 0 0 0 % D
% Glu: 0 0 0 8 0 8 0 8 0 16 8 8 16 0 0 % E
% Phe: 0 16 0 0 31 8 8 0 0 8 0 0 0 0 0 % F
% Gly: 8 0 8 8 0 0 0 8 0 0 0 0 0 0 8 % G
% His: 0 0 0 39 8 0 0 0 0 0 8 8 8 0 0 % H
% Ile: 0 16 16 0 8 0 8 8 0 0 0 0 24 0 0 % I
% Lys: 8 0 8 8 8 0 39 0 39 0 0 8 0 16 8 % K
% Leu: 39 16 0 8 24 0 8 8 0 16 54 8 0 24 0 % L
% Met: 0 0 0 0 0 0 0 0 8 8 16 0 8 0 0 % M
% Asn: 8 0 0 0 0 8 0 0 8 0 0 0 0 0 8 % N
% Pro: 8 0 0 0 0 16 8 8 0 0 0 8 0 8 0 % P
% Gln: 0 39 39 0 0 0 0 0 0 0 8 8 0 0 16 % Q
% Arg: 0 0 0 8 0 0 8 0 8 0 0 39 8 0 8 % R
% Ser: 16 8 0 0 0 16 8 54 8 0 0 8 16 24 16 % S
% Thr: 0 0 0 8 16 0 0 0 8 8 8 8 0 8 31 % T
% Val: 0 0 16 0 0 0 8 8 0 0 0 0 24 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 0 0 8 8 8 0 0 8 0 0 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _